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Oxidative Stress and Neuropsychiatric Disorders Neuropsychiatric disorders are complex and heterogeneous disorders that not only negatively impact quality of life but also significantly affect behavior and cognitive functions (Post, 1992

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On the other hand, other authors have shown that MPP + induces negative effects in astrocytes, such as loss of viability, impairment of energetic metabolism of mitochondria, ROS generation and decrease in the glutamate clearance by astrocytes [81,85,86]